美國BD公司Purified Mouse anti-TAZ抗體Clone M2-616

美國BD公司Purified Mouse anti-TAZ抗體Clone M2-616

規(guī)格

0.1 mg

貨號(hào)

560235

目錄價(jià)

¥ 5,543.00

Brand

BD Pharmingen™

Alternative Name

WWTR1

Concentration

0.5 mg/ml

Isotype

Mouse BALB/c IgG2b, κ

Reactivity

Human (QC Testing)  Mouse (Tested in Development) 

Application

Western blot (Routinely Tested) 
Bioimaging (Tested During Development) 

Immunogen

Human TAZ Recombinant Protein

Storage Buffer

Aqueous buffered solution containing ≤0.09% sodium azide.

詳細(xì)說明：

DESCRIPTION

Taz is a 49-kDa transcriptional co-activator with a PDZ-binding motif and is regulated by binding with 14-3-3 proteins. It plays a key role in differentiation of mesenchymal stem cells into either osteoblasts or adipocytes via interactions with key transcription factors Runx2 and PPAR γ . More recently, Taz was found to be a component of an E3 ubiquitin ligase involved in ubiquitin-dependent substrate proteolysis by mediating its interaction with the F-box protein β -Trcp. Therefore, Taz has dual functions of regulating protein degradation and transcription.

FORMAT

Format

Purified

SUGGESTED COMPANION PRODUCTS

RESOURCES & TOOLS

• Download TDS

PREPARATION AND STORAGE

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C.

PRODUCT NOTICES

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to www.bdbiosciences。。ｃｏｍ/pharmingen/protocols for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Triton is a trademark of the Dow Chemical Company.
5. This antibody has been developed and certified for the bioimaging application. However, a routine bioimaging test is not performed on every lot. Researchers are encouraged to titrate the reagent for optimal performance.